Which Vape Coils Work Best with High VG, 50/50 and Nic Salt e-liquids?
August 29, 2025Your e-liquid and vape coil need to work as a team. High-VG liquids demand different vape coil specifications than nicotine salts, and using the wrong combination leads to poor wicking, muted flavours, or harsh hits that nobody wants to experience.
One of the most common mistakes vapers make is choosing coils without considering their e-liquid type. Yet the relationship between e-liquid composition and coil design is fundamental to getting great performance from your setup.
Different e-liquid types have vastly different viscosities, heating requirements, and optimal power ranges. What works perfectly with a thick high-VG liquid will likely perform poorly with nicotine salts, and vice versa. Understanding these relationships helps you avoid frustrating experiences like dry hits, leaking, or flavours that never quite taste right.
Whether you're using high-VG liquids for cloud production, 50/50 blends for versatility, or nicotine salts for satisfaction, the right coil choice makes all the difference.
Key Takeaways
- High-VG e-liquids (70VG/30PG+) require low-resistance coils with large wicking ports and higher wattages
- 50/50 e-liquids offer the most coil compatibility, working well with MTL, RDL, and some DTL setups
- Nicotine salt e-liquids perform best with higher-resistance MTL coils at lower wattages
- Coil wicking capacity must match e-liquid thickness to prevent dry hits or flooding
- Wrong e-liquid/coil combinations lead to poor flavour, reduced coil life, and device issues
- Knowing your e-liquid's VG/PG ratio helps you choose the right coil for optimal flavour and performance
Premium replacement mesh coils for the Lost Vape Centaurus Sub-Ohm Tank, available in 0.15ohm, 0.2ohm, and 0.3ohm DTL resistances.
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Lost Vape Lost Vape UB Max Replacement Coils
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RDL (Restricted-Direct-to-Lung): A balanced vaping style slightly restricted airflow.
Mesh coils for PZPulse Pods in 0.2ohm, 0.4ohm, and 0.6ohm for MTL, RDL, and DTL vaping.
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Innokin Innokin PZP Max Replacement Coils
£4.49
Smok D-Coil Meshed Replacement Coils – Available in 0.15ohm, 0.23ohm, and 0.4ohm, designed for DTL and RDL vaping styles with...
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SMOK SMOK D-Coils - 5 Coils
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Innokin Endura Prism T18/T22 Coils, 5-pack of replacement MTL coils, compatible with the Innokin Endura Kit and T18 & T22...
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Innokin Innokin Endura Prism T18/T22 Coils
£4.99
Replacement Coils for the SMOK RPM 5 Pod Kit x 5
£9.99
SMOK SMOK RPM 3 Coils - Pack x 5
£9.99
Classic Coils for the Prism Tank: 1.5 or 2.0 Ohms
£4.49
Innokin Innokin Endura T18E Coils
£4.49
DTL (Direct-to-Lung): Vapour is inhaled directly into the lungs for larger clouds of vapour.
Smok RPM Coils
£6.49
SMOK SMOK RPM Replacement Coils
£6.49
Pack of 5 Nautilus BVC Replacement coils.
£6.99
Aspire Aspire Nautilus BVC Replacement Coils
£6.99
High-performance mesh coils featuring Z XM Boost technology for extended lifespan, rich flavour, and massive cloud production.
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Geekvape Geekvape Z Series Coils
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Aspire PockeX Replacement Coils 5 Pack for PockeX AIO Kit or PockeX Box kit
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Aspire Aspire PockeX Replacement Coils - 5 Pack
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What's the Difference Between High-VG, 50/50 and Nic Salt E-Liquids?
VG/PG Ratios Explained
VG (Vegetable Glycerin) is thick, sweet, and produces dense vapour. PG (Propylene Glycol) is thinner, carries flavour better, and provides throat hit. The ratio between these two base ingredients determines how your e-liquid behaves in different coils.
High-VG liquids (70VG/30PG and above) are viscous and require more power to vaporise effectively. They produce substantial vapour clouds but need coils designed to handle thick liquids.
50/50 blends balance vapour production with flavour delivery. Their moderate thickness works across a wider range of coil types and power settings.
How Do Nicotine Types Affect Vape Coil Choice?
Nicotine salts use a different chemical structure that allows higher nicotine concentrations without harshness. Almost all nic salts now use a 50VG/50PG ratio, but their coil requirements differ significantly from freebase 50/50 liquids due to the nicotine formulation and intended vaping style.
Freebase nicotine (traditional nicotine) provides a throat hit that increases with strength. It's commonly found in both 50/50 and high-VG liquids.
These sub ohm coils from Eleaf are available as: 0.3 or 0.5 Ohms
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Eleaf Eleaf EC Atomizer Head
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Sub-ohm coils for TFV8 X-Baby tank: 0.13 Ohms
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SMOK SMOK V8 X-Baby X4 Quad Core Sub-Ohm Coils
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Aspire Aspire Nautilus 2S Sub Ohm Coils 0.4 Ohm
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Coils for the Smok Stick Series 0.15ohm
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SMOK SMOK S1 Baby V2 Single Mesh Sub Ohm Coils 0.15 Ohm
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Designed for use with the TFV12 Prince Tank (Pack of 3)
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SMOK SMOK TFV12 Prince-Q4 Sub Ohm Coils
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These sub ohm coils are designed for use with the Mesh Pro Tank: 0.15 Ohm
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Freemax Freemax Mesh Pro 0.15 Ohm Triple Mesh Sub Ohm Coils
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RDL (Restricted-Direct-to-Lung): A balanced vaping style slightly restricted airflow.
DTL (Direct-to-Lung): Vapour is inhaled directly into the lungs for larger clouds of vapour.
5 x pack replacement coils
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Vaporesso Vaporesso GTX Replacement Coils
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Which Coils Should I Use with High-VG E-Liquids?
High-VG e-liquids are the go-to choice for cloud chasers and DTL vapers. But their thick consistency demands specific vape coil characteristics.
Sub-ohm coils (below 0.5ohm) are essential for high-VG liquids. Lower resistance allows higher power output, which generates the heat needed to properly vapourise thick VG. Popular ranges include 0.15-0.2ohm for maximum clouds, 0.3-0.4ohm for balanced performance, and moderate sub-ohm coils (0.3-0.5ohm) for those new to higher-power vaping.
High-VG liquids need large wicking ports and substantial cotton capacity. The coil must draw thick liquid efficiently to prevent dry hits during extended sessions. Mesh coils excel here - their larger surface area and improved wicking design handle viscous liquids better than traditional wire coils.
These setups typically operate between 40-100W+, ensuring complete vapourisation and consistent performance.
Browse our sub-ohm coils designed specifically for high-VG performance.
Why Are 50/50 E-Liquids So Versatile?
The balanced VG/PG ratio creates a "goldilocks" liquid - not too thick, not too thin. This moderate viscosity wicks effectively in both high and low-resistance coils.
Important note: 50VG/50PG has become the default ratio for nearly all e-liquids today, including both traditional freebase nicotine and nicotine salt formulations. The key difference isn't the VG/PG ratio, but rather the nicotine type used.
Compatible coil resistance ranges:
- MTL coils (0.8-1.4ohm): Work perfectly for mouth-to-lung vaping
- RDL coils (0.4-0.8ohm): Provide balanced performance
- Moderate sub-ohm coils (0.3-0.5ohm): Suitable for moderate cloud production
50/50 liquids perform well across 10-50W depending on coil resistance. This flexibility means you're not locked into specific power requirements, making them perfect for new vapers learning preferences, all-day vaping where battery life matters, and switching between different devices.
What Coils Work Best with Nicotine Salts?
Nicotine salts aren't just about higher nicotine content - they're formulated to work optimally with specific coil types designed for mouth-to-lung vaping.
Higher resistance coils (0.8-1.4ohm) operating at 10-15W prevent overheating the nicotine salt formulation, which can create harshness despite the smoother delivery. These coils typically include tighter airflow designs that mimic cigarette draw resistance.
Nic salts are generally gentler on coils than high-VG liquids due to lower power requirements and thinner consistency, often extending coil lifespan. Check out our classic MTL coils optimised for nicotine salt performance.
DTL (Direct-to-Lung): Vapour is inhaled directly into the lungs for larger clouds of vapour.
Replacement PNP coils
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VooPoo VooPoo PNP Coils
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Classic Coils for the Prism Tank: 1.5 or 2.0 Ohms
£4.49
Innokin Innokin Endura T18E Coils
£4.49
Replacement Aspire TG Fixed-Coil 1.0ohm 2ml pods for the Aspire Cyber G vape kit x 2
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Aspire Aspire TG Replacement Fixed Coil Pods - 2 Pack
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RDL (Restricted-Direct-to-Lung): A balanced vaping style slightly restricted airflow.
DTL (Direct-to-Lung): Vapour is inhaled directly into the lungs for larger clouds of vapour.
Aspire AF Mesh Replacement Coil x 5
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Aspire Aspire Flexus AF Mesh Coils x 5
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SMOK SMOK LP1 Replacement Coils
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Innokin Endura Prism T18/T22 Coils, 5-pack of replacement MTL coils, compatible with the Innokin Endura Kit and T18 & T22...
£4.99
Innokin Innokin Endura Prism T18/T22 Coils
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DTL (Direct-to-Lung): Vapour is inhaled directly into the lungs for larger clouds of vapour.
SMOK Nord Pro Replacement Coils (5 Pack)
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SMOK SMOK Nord Pro Replacement Coils - 5 Pack
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What Happens When I Use the Wrong E-liquid and Coil Combination?
Using High-VG in MTL Coils: What Can Go Wrong
Thick high-VG liquid can't wick properly through small MTL coil ports, resulting in dry hits, burnt taste, and rapid coil failure. Solution: Use sub-ohm coils with larger wicking capacity for high-VG liquids.
Nic Salts in High-Power Coils: Too Much Heat
High wattages overheat nicotine salt formulations, creating harsh throat hit and unpleasant taste. Solution: Stick to MTL coils operating at 10-15W for nic salts.
50/50 Liquids in Cloud-Chasing Setups
At high power, 50/50 e-liquids may not deliver the vapour output some vapers expect, and can vaporise too quickly or become harsh at high wattages. Solution: Use 50/50 liquids in moderate power ranges (15-40W) for best balance.
How Should I Prime Coils for Different E-Liquid Types?
When using replaceable coils, pay special attention to the your vape coil type so that you can prime it correctly.
- High-VG liquids need extra attention: Apply 5-7 drops directly to cotton, wait 10-15 minutes after filling, start at 50% recommended wattage, and take longer breaks between initial puffs.
- 50/50 and nic salt liquids use standard priming: 2-3 drops on visible cotton, 5-10 minute saturation time, start low and increase gradually.
Are Prefilled Pod Coils Designed for Specific E-Liquids?
Most prefilled pod systems use nicotine salt formulations in 50/50 ratios with built-in coils (typically 0.6-1.2ohm) optimised for these liquid types. This gives perfect liquid/coil matching by the manufacturer with no guesswork about compatibility. High-VG prefilled options are rare and typically designed with specialised coils for higher power output.
Can I Switch E-Liquid Types with the Same Coil?
Generally not recommended. Different e-liquid types can leave residual flavours, create wicking issues if viscosities vary significantly, and reduce coil performance.
If you must switch: Use similar VG/PG ratios, clean your tank thoroughly, consider a fresh coil for dramatically different liquid types, and allow extra priming time when switching to thicker liquids.
Not sure which coils fit your device? Try our Coil Finder Tool to match your setup with compatible options in seconds.
Premium replacement mesh coils for the Lost Vape Centaurus Sub-Ohm Tank, available in 0.15ohm, 0.2ohm, and 0.3ohm DTL resistances.
£6.49
Lost Vape Lost Vape UB Max Replacement Coils
£6.49
RDL (Restricted-Direct-to-Lung): A balanced vaping style slightly restricted airflow.
Mesh coils for PZPulse Pods in 0.2ohm, 0.4ohm, and 0.6ohm for MTL, RDL, and DTL vaping.
£4.49
Innokin Innokin PZP Max Replacement Coils
£4.49
Smok D-Coil Meshed Replacement Coils – Available in 0.15ohm, 0.23ohm, and 0.4ohm, designed for DTL and RDL vaping styles with...
£8.99
SMOK SMOK D-Coils - 5 Coils
£8.99
Innokin Endura Prism T18/T22 Coils, 5-pack of replacement MTL coils, compatible with the Innokin Endura Kit and T18 & T22...
£4.99
Innokin Innokin Endura Prism T18/T22 Coils
£4.99
Replacement Coils for the SMOK RPM 5 Pod Kit x 5
£9.99
SMOK SMOK RPM 3 Coils - Pack x 5
£9.99
Classic Coils for the Prism Tank: 1.5 or 2.0 Ohms
£4.49
Innokin Innokin Endura T18E Coils
£4.49
DTL (Direct-to-Lung): Vapour is inhaled directly into the lungs for larger clouds of vapour.
Smok RPM Coils
£6.49
SMOK SMOK RPM Replacement Coils
£6.49
Pack of 5 Nautilus BVC Replacement coils.
£6.99
Aspire Aspire Nautilus BVC Replacement Coils
£6.99
High-performance mesh coils featuring Z XM Boost technology for extended lifespan, rich flavour, and massive cloud production.
£8.99
Geekvape Geekvape Z Series Coils
£8.99
Aspire PockeX Replacement Coils 5 Pack for PockeX AIO Kit or PockeX Box kit
£10.99
Aspire Aspire PockeX Replacement Coils - 5 Pack
£10.99
Conclusion
Getting the e-liquid and vape coil combination right isn't complicated once you understand the basics. High-VG liquids need low-resistance coils and higher power. Nicotine salts work best with higher-resistance MTL setups. And 50/50 blends offer flexibility across most coil types.
The key is matching viscosity to wicking capacity and power requirements to liquid type. Get this right and you'll enjoy better flavour, longer coil life, and a more satisfying vaping experience overall.
Matching the right coil to your chosen e-liquid ensures optimal flavour, vapour, and device performance. If you want to dive deeper into coil compatibility and selection, check our full guide: How to Choose the Right Vape Coils.
Ready to find your perfect combination? Explore our e-liquid collection and coils to discover what works best for your setup. Need help choosing? Our Customer Services Team can recommend the ideal e-liquid and coil pairing for your device and preferences.